Polynucleotides, often referred to as “salmon sperm DNA” or PDRN/PN therapy, represent the latest breakthrough in regenerative aesthetic medicine. Unlike traditional injectables that simply fill or smooth, Polynucleotides work at a cellular level — stimulating deep skin repair, hydration, and renewal for long-term rejuvenation.

Mechanism & Formula

Polynucleotides are highly purified DNA fragments extracted from salmon sperm cells, chosen for their remarkable biocompatibility and regenerative power.

These nucleic acid chains act as natural bio-stimulators — encouraging fibroblasts to produce new collagen, elastin, and extracellular matrix components, thereby rebuilding the skin’s structure from within.

Their anti-inflammatory and antioxidant properties enhance tissue oxygenation, microcirculation, and overall skin vitality — making them an exceptional treatment for restoring youthful tone and radiance.

Key Benefits

Deep, long-lasting hydration that restores skin plumpness and elasticity
Improves firmness, density, and structural resilience
Smooths fine lines and enhances overall texture
Brightens and rejuvenates the under-eye area, reducing dark circles, hollowness, and tired appearance
Stimulates collagen and elastin for long-term skin regeneration
Promotes healing, radiance, and natural luminosity
Safe, biocompatible, and suitable for all skin types

Polynucleotides are particularly effective for delicate areas such as the eyes, where traditional fillers may be too heavy or risky. The treatment restores volume and vitality naturally, leaving the skin firmer, brighter, and more youthful.

Treatment Protocol & Maintenance

A full treatment typically includes two to three sessions, spaced three to four weeks apart, depending on individual needs and skin condition.

To maintain optimal results, a maintenance session every 3-6 months is recommended.

Results

After completing the recommended course, clients experience visibly rejuvenated skin — firmer, smoother, and deeply hydrated. Fine lines are softened, texture is refined, and the under-eye area looks refreshed and well-rested.

Polynucleotides offer a unique, natural, and science-backed approach to regeneration — rebuilding the skin’s foundation for lasting beauty.